19 Polymer Micelles for Drug Delivery

نویسندگان

  • Sungwon Kim
  • Kinam Park
چکیده

Polymer micelles have been used widely in the delivery of various therapeutic drugs, which are also known as active pharmaceutical ingredients (APIs). Recent advances in drug discovery technology, including an accumulated database on therapeutic targets, combinational chemistry, and high-throughput screening (HTS), have further increased the number of candidate compounds and constructed a huge pipeline for the discovery and development of new chemical entities (NCEs).1,2 A very large number of chemicals are hailed as new drug candidates, but almost one-third of them are poorly water soluble.3 Polymer micelles consisting of amphiphilic CONTENTS

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تاریخ انتشار 2010